SxC6C
This library follows the pattern SXCXXXXXXC. The 48HD SXC6C-DCA library is a monocyclic peptide library. Formed from the post translational cyclization of a linear SXCXXXXXXC (where X is a natural amino acid with the exception of cysteine) library with a dichloroacetone linker. The library has a diversity of approximately 1 x 109 unique sequences. The 48HD SXC6C-MBX library is a monocyclic peptide library. Formed from the post translational cyclization of a linear SXCXXXXXXC (where X is a natural amino acid with the exception of cysteine) library with a met-bromo xylene linker. The library has a diversity of approximately 1 x 109 unique sequences. The 48HD SXC6C-TSL library is a bicyclic peptide library. Formed from the post translational cyclization of a linear SXCXXXXXXC (where X is a natural amino acid with the exception of cysteine) library with a proprietary two-fold symmetric linker. The library has a diversity of approximately 1 x 109 unique sequences.
This library has been screened 9 times as Naive library or Operational stock, and 25 times in panning experiments.
Theoretical Library, Naive and OS Screenings
Panning Screenings